What impacts that permeability? NSAIDs, antibiotics, acid-blocking drugs such as Nexium and pesticide Roundup all change our gut flora and the mucous layer of our gut. This compromises the barrier of our intestines on a daily basis, thereby allowing lectins in.
Copious research over the last half century reveals that gulping down NSAIDs is like swallowing a live grenade. These drugs blow gaping holes in the mucus-lined intestinal barrier. As a result, lectins, LPSs, & living bacteria are able to deluge the breaks in your gut, flooding your body with foreign invaders. And this confluence of forces prompts our immune system to unleash an attack on ourselves, in a classic case of mistaken identity caused by molecular mimicry.
In fact, much of what we assume as a normal part of the aging process is actually the cumulative effect of Lectin toxicity.
Ref: Plant Paradox by Steven Gundry