What are the other biomarkers of CV risk?
HDL-C (High density lipoprotein-cholesterol)
is one of the best biomarkers of long term cardiovascular health. Low levels indicate significant cardiovascular risk independent of LDL-C. HDL-C acts as a scavenger of excess cholesterol from lipoproteins and tissues requiring transport back to liver (reverse cholesterol transport).
TG/HDL-C ratio
Studies indicate that the TG/HDL-C ratio is highly associated with insulin resistance. This ratio is comparable to the ATP III criteria for metabolic syndrome in predicting insulin resistance and even better in prediction of the LDL pattern B
phenotype in one study. A TG/HDL-C ratio 3.5 has been suggested as a cutoff for identifying the insulin-resistant patient most at risk for cardiovascular disease.
is one of the best biomarkers of long term cardiovascular health. Low levels indicate significant cardiovascular risk independent of LDL-C. HDL-C acts as a scavenger of excess cholesterol from lipoproteins and tissues requiring transport back to liver (reverse cholesterol transport).
TG/HDL-C ratio
Studies indicate that the TG/HDL-C ratio is highly associated with insulin resistance. This ratio is comparable to the ATP III criteria for metabolic syndrome in predicting insulin resistance and even better in prediction of the LDL pattern B
phenotype in one study. A TG/HDL-C ratio 3.5 has been suggested as a cutoff for identifying the insulin-resistant patient most at risk for cardiovascular disease.