瘦的人血糖也正常是否可能有胰島素抗性
糖尿病病人和葡萄糖不耐的患者大部分都有胰島素抗性但值得注意的是葡萄糖耐受性測驗（oral glucose tolerance test) 正常且無肥胖症的人群中約 25％有胰島素抗性 [1]。這25％族群中有些人的胰島素抗性程度和葡萄糖不耐的或糖尿病病人的胰島素抗性程度是相似的。胰島素抗性是代謝症候群的主要特徵故葡萄糖耐受性測驗正常而且無肥胖症不代表慢性病不會上身。他們如果長期攝取大量的高升糖指數食物（例如蔗糖）10年後可能會罹患 高血壓，糖尿病，中風，冠心病，癌症等 5 種疾病其中一樣。臨床上如何來偵測胰島素抗性呢？一個比較簡單的方法為三酸甘油脂／高密度脂蛋白膽固醇之比值（TG/HDL-C Ratio) 大於 3.5 代表有胰島素抗性也同時是心血管疾病的高危險群 [2]。
參考文獻
[1] Reaven GM: Banting lecture 1988. Role of insulin resistance in human disease. Diabetes 1988;37:1595-607.
For abstract, go to the following link:
http://www.ncbi.nlm.nih.gov/pubmed?term=%22Diabetes%22%5BJour%5D+AND+37%5Bvolume%5D+AND+1595%5Bpage%5D+AND+1988%5Bpdat
%5D&cmd=detailssearch
[2] McLaughlin T, Reaven G, et al Is there a simple way to identify insulin-resistant individuals at increased risk of cardiovascular disease? Am J Cardiol 2005;96:399-404.
For abstract, go to the following link:
http://www.ncbi.nlm.nih.gov/pubmed?term=%22The+American+journal+of+cardiology%22%5BJour%5D+AND+96%5Bvolume%5D+AND+399%5Bpage%5D+AND+2005%5Bpdat%5D&cmd=detailssearch
參考文獻
[1] Reaven GM: Banting lecture 1988. Role of insulin resistance in human disease. Diabetes 1988;37:1595-607.
For abstract, go to the following link:
http://www.ncbi.nlm.nih.gov/pubmed?term=%22Diabetes%22%5BJour%5D+AND+37%5Bvolume%5D+AND+1595%5Bpage%5D+AND+1988%5Bpdat
%5D&cmd=detailssearch
[2] McLaughlin T, Reaven G, et al Is there a simple way to identify insulin-resistant individuals at increased risk of cardiovascular disease? Am J Cardiol 2005;96:399-404.
For abstract, go to the following link:
http://www.ncbi.nlm.nih.gov/pubmed?term=%22The+American+journal+of+cardiology%22%5BJour%5D+AND+96%5Bvolume%5D+AND+399%5Bpage%5D+AND+2005%5Bpdat%5D&cmd=detailssearch